Mon | Nov 20, 2017

UN health agency urges early action to stave off threat of HIV drug resistance in the Caribbean

Published:Sunday | July 23, 2017 | 11:06 AM

UNITED NATIONS, CMC –The United Nations health agency has warned that the spread of an HIV strain resistant to some of the most widely used medicines could undermine global progress in treating and preventing HIV infection in the Caribbean and other places if early and effective action is not taken.

“Antimicrobial drug resistance is a growing challenge to global health and sustainable development,” said Tedros Adhanom Ghebreyesus, the Director-General of the World Health Organization (WHO) on Friday.

We need to proactively address the rising levels of resistance to HIV drugs if we are to achieve the global target of ending AIDS by 2030,” he added.

According to the WHO  HIV drug resistance report 2017,  in six of the 11 countries surveyed in Africa, Asia and Latin America and the Caribbean, more than 10 per cent of people starting antiretroviral therapy had a strain that was resistant to some of the most widely used medicines.

Once the threshold of 10 per cent has been reached, WHO recommends those countries urgently review their HIV treatment programmes.

HIV drug resistance develops when people do not adhere to a prescribed treatment plan.

Those with drug resistance will start to fail therapy and may also transmit drug-resistant viruses to others, the UN said.

Of the 36.7 million people living with HIV worldwide, 19.5 million people were accessing antiretroviral therapy in 2016, the UN said.

It said the majority of these people are doing well, but the number of those experiencing the consequences of drug resistance is growing.

The UN said increasing HIV drug resistance trends could lead to more infections and deaths.

Mathematical modelling shows an additional 135,000 deaths, and 105,000 new infections could follow in the next five years if no action is taken, and HIV treatment costs could increase by an additional US$650 million during this time, according to the UN.

WHO is, therefore, issuing new guidelines to help countries address HIV drug resistance.

“When levels of HIV drug resistance become high, we recommend that countries shift to an alternative first-line therapy for those who are starting treatment,” said Gottfried Hirnschall, director of WHO’s HIV Department and Global Hepatitis Programme.

Meanwhile, a new United Nations report says the scales have tipped for the first time in the fight against AIDS, as more than half of all people living with the HIV virus in the Caribbean and other places now have access to treatment, while AIDS-related deaths have nearly halved since 2005.

“We met the 2015 target of 15 million people on treatment and we are on track to double that number to 30 million and meet the 2020 target,” said Michel Sidibé, the Executive Director of the Joint UN Program on HIV/AIDS (UNAIDS), on Thursday.

“We will continue to scale up to reach everyone in need and honour our commitment of leaving no one behind,” he added.