JetBlue airline is to start daily round trips between New York's John F Kennedy International and Cuba’s Jose Marti International, Havana come November 28.

The airline will be the first US carrier to bring scheduled service to Cuba after more than 50 years.

The airline's historic first flight to Cuba kicks off a new era in travel, said Robin Hayes, president and chief executive officer, JetBlue.

“It’s remarkable that a startup airline less than 17 years old will mark Havana as its 100th destination,” added Hayes.

A day after the flights begin from New York to Cuba, JetBlue will start non-stop service to Havana from Orlando and then on November 30, to Havana from Fort Lauderdale.

“JetBlue continues to make Cuba more affordable for those who meet government travel requirements," a JetBlue spokesperson said in a release.

It's announced rates include Cuban government-required health insurance coverage.